From Molecules to Patients, From Mechanisms to Treatments: Neuropathic Pain in Its Global Year

SIG Name: Neuropathic Pain (NeuPSIG)

Description of Symposium: While IASP puts a special focus on neuropathic pain through the “Global Year”, we want to shine an interdisciplinary light on the continued challenge of understanding and treating an elusive condition. As evidenced in our 2025 updated guidelines, effective and safe treatments are still missing, with well-established medications only leading to sufficient pain relief in a fraction of patients. In this satellite, we aim to bring together all parts of the NeuPSIG, from bench scientists to clinicians, from senior leaders of the field to early career scientists.
The symposium will be structured into three main blocks: updates from mechanistic studies and understanding neuropathic pain in the lab; translating knowledge from cells and animal studies to humans; and applying state-of-the-art understanding to treating patients (non-)pharmacologically.
Each block will be chaired by a senior leader of the field and the NeuPSIG. We will have four brief presentations for each block, allowing for a fully balanced mix covering geographical, gender-, and career-level representation. We will recruit this speaker team through the NeuPSIG congress 2025 and by reviewing poster abstracts for the World Congress.

Intended Audience: Cross-disciplinary, Clinical Research, Translational Research, Basic Science

Educational Objectives:

• List state-of-the-art approaches to unravel the molecular mechanisms of neuropathic pain,
• Describe challenges and advances in translating these into human studies,
• Outline the best pharmacological and non-pharmacological management strategies for neuropathic pain, and how they are informed by mechanistic research.

Speakers