449: Effectiveness of Pain Management in Patients with Chronic Cancer Pain in a Tertiary Care Hospital

Topic: Clinical Science
Subtopic: Pain category (ICD-11), Chronic cancer related pain, Pharmacological treatments, Treatment/management

Background and Aims: Background and aims:
Pain is one of the most prevalent and distressing symptoms experienced by patients with cancer, particularly those with advanced malignancies. Pain management strategies in cancer patients include a range of pharmacologic, non-pharmacologic modalities and pain intervention procedures.
Aim of the study was to observe the effectiveness of pain management techniques, character and severity of pain, frequency of pain intervention procedures, and side effects in patients with chronic cancer pain presenting to pain management clinic.

Methods: After getting approval from the Institutional review committee (ERC # 2025-12152-38344), retrospective study was conducted in the pain management clinic of Aga Khan University Hospital, Karachi.
All adult patients of both genders with cancer pain presenting to the pain management clinic during study period were included. All data were recorded from patient’s medical record and online patient management system.
Every patient was followed for three months after the initial visit and required data was recorded.

Results: 134 patients with chronic cancer pain were included in this study. Mean age of patients was 54.6 ± 16.2 years, and 56.72% were male. At initial presentation, majority of patients had mixed pain (58.21%), 14.93%, nociceptive and 26.87% had neuropathic pain. 72.4% of patients had severe and 27.6% had moderate intensity of pain. Conservative management was used in 105 (78%) of patients.
Pain interventional procedures were performed in 29 (22%) patients.
Significant reduction in pain scores was observed following pain management interventions. Mean pain scores showed more than 50% reduction three months after treatment.

Conclusions: Pain management techniques provided to chronic cancer patients were effective as shown by statistically significant reduction in pain score.
Frequency of pain intervention procedure was 22%, without any significant side effects.

References: References:
1. Wangnamthip S, Panchoowong S, Donado C, Lobo K, Phankhongsap P, Sriveerachai P, Euasobhon P, Rushatamukayanunt P, Mandee S, Zinboonyahgoon N, Berde CB. The effectiveness of cancer pain management in a tertiary hospital outpatient pain clinic in Thailand: A prospective observational study. Pain Research and Management. 2021;2021(1):5599023.
2. Sharma A, Thakur N, Thakur A, Bhardwaj N. Role of interventional techniques in the management of cancer pain. Asian Pacific Journal of Cancer Care. 2023 Jun 14;8(2):391-9.

Presenting Author: ALI SARFRAZ SIDDIQUI
Submitting Author: Ali Sarfraz Siddiqui

Senior Author: GAUHAR AFSHAN

IASP 2026 Global Year theme of Neuropathic Pain: No

• ASIF HASSAN: FCPS - Aga Khan University,
• ABDULLAH NISAR: FCPS - Aga Khan University
• ROZINA KERAI: MSc - Aga Khan University
• GAUHAR AFSHAN: FCPS - Aga Khan University