455: Efficacy and Safety: Autologous PRP+MT in Scapulohumeral Periarthritis

Topic: Clinical Science
Subtopic: Pain category (ICD-11), Chronic primary musculoskeletal pain, Developing methodology/technology, Pharmacological treatments, Treatment/management

Background and Aims: Objective:
To investigate the efficacy and safety of autologous platelet-rich plasma (PRP) combined with manual therapy in the treatment of scapulohumeral periarthritis.

Methods: Method:
From January 2020 to December 2021, 80 patients with scapulohumeral periarthritis in the First People's Hospital of Zhaoqing were selected and randomly divided into an observation group and a control group, with 40 cases in each group. The control group was treated with manual treatment, and the observation group was treated with autologous PRP local injection on the basis of the control group. After the treatment, Constant-Murley shoulder function score, pain score and clinical efficacy were compared between the two groups.

Results: Result：
At 4 weeks, pain was lower in observation vs control (P<0.05). At 6 months, Constant-Murley scores increased in both groups vs baseline, with observation higher (P<0.05). Total efficacy: 87.50% vs 65.00% (P<0.05). Adverse events: 10.00% vs 7.50% (P>0.05).

Conclusions: Conclusion:
Autologous PRP combined with manual therapy in the treatment of scapulohumeral periarthritis can not only effectively relieve the clinical symptoms and
pain, but also improve the shoulder joint function of patients, with good safety.

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Presenting Author: Yinghao Ou
Submitting Author: Yinghao Ou

Senior Author: Yinghao Ou

IASP 2026 Global Year theme of Neuropathic Pain: No